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WORLD SOCIETY OF THE
ABDOMINAL COMPARTMENT SYNDROME

WSACS-Sponsored Clinical Research Trials

The Clinical Trials Working Group (CTWG) of the World Society on Abdominal Compartment Syndrome (WSACS) sponsors high-quality research and education in the fields of intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS). If you are interested in participating in CTWG-sponsored research trials, please complete the CTWG Investigator Interest Form so that we may keep you updated as to the status of CTWG-sponsored research,

The clinical trials listed below are currently recruiting patients. Investigators who are interested in becoming a study site for one or more of these studies should contact the Primary Investigator listed for each trial.

Please contact the CTWG chairman Dr. Jan DeWaele with any questions or concerns regarding these studies.


Active Clinical Trials


Trial NumberWSACS002
Date Submitted1156824000
TitleAbdominal Hypertension and Rectus Sheath or Retroperitoneal Hematoma: A Multicenter Retrospective Analysis
Primary InvestigatorManu Malbrain, MD
Contact Emailmanu.malbrain@skynet.be
Summary
Rectus sheath or retroperitoneal hematoma is a well recognised complication of treatment with low molecular weight heparin (LMWH) or oral anticoagulation, but can also be caused by trauma, after surgery, with pregnancy or just spontaneously. Increased intra-abdominal pressure (IAP) and abdominal compartment syndrome (ACS) have recently been reported as a complication of LMWH-associated rectus sheath hematoma and in some cases surgical evacuation resulted in improvement of organ function. Primary objective: To determine the effect of intervention/surgery on the clinical course of patients with rectus sheath or retroperitoneal hematoma. Secondary objective: To determine the clinical course of patients with rectus sheath or retroperitoneal hematoma without decompressive surgery.
DocumentationStudy Protocol





Completed Clinical Trials


Trial NumberWSACS001
Date Submitted1150430400
TitleThe Effect of Body Positioning on Intra-Abdominal Pressure Measurement: A Multicenter Analysis
Primary InvestigatorMichael L. Cheatham MD, Jan J. DeWaele MD,
Contact Emailmichael.cheatham@orhs.org
Summary


Trial NumberWSACS003
Date Submitted1156824000
TitleSurvey on the Clinical Awareness of Intra-abdominal Hypertension (IAH) and the Abdominal Compartment Syndrome (ACS) in Critically Ill Patients
Primary Investigator WSACS Executive Committee,
Contact Emailwebmaster@wsacs.org
SummaryThis survey is designed to assess the clinical awareness of IAH and ACS in intensive care units and emergency departments around the world, and to determine when and how IAP is measured and IAH and ACS are managed. Although there is strong evidence supporting the deleterious effects of increased intra-abdominal pressure (IAP), intra-abdominal hypertension (IAH), and abdominal compartment syndrome (ACS) in different patient populations, the measurement of IAP is not yet universally applied even among those patients where the evidence is most strong. The WSACS Executive Committee has created an interactive online survey to characterise the current worldwide understanding and application of IAP monitoring and management of IAH and ACS among multidisciplinary critical care providers. This survey has been endorsed by the European Society of Intensive Care Medicine (ESICM) and is approved by the Orlando Regional Healthcare Institutional Review Board.








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